The relationship between climatology and obsessive-compulsive disorder (OCD) has not been sufficiently considered and the gaps have been left unfilled. This article aimed at finding the relationship between climatology and behavior setting in OCD patients. The current study is a descriptive relational study based on a literature review. Eleven databases from four related disciplines were searched, including interdisciplinary, health, Iranian Red Crescent Medical Journal (Ircmj) and Iranian medical university. Of the 1960 papers identified, 39 met the eligibility criteria and quality for selection from different geographic regions all over the world. Findings indicate different climatic conditions lead to variable OCD prevalence rate. The most frequent OCD patients are related in cold and dry climatic conditions. Also the lowest frequency OCD patients are related in hot and humid weather and climatology. There are clear relationship between climatology and OCD prevalence. And this is in line with the theory of Avicenna. To develop and elaborate the studies based on the friendly environment principle besides including the results of this investigation based on Avicenna theory. Further investigation is recommended to find the direction of relationship between two important factors.

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